Vitalspell — Evidence-based supplement science

Can gut bacteria predict bone loss in hyperparathyroidism?

Gut bacteria may flag bone loss in hyperparathyroidism, but the new Bone Research paper is still an early risk signal, not probiotic advice.

Priya Nair· 8 min read

Sleep

Can vitamin D help you sleep? What the evidence says

Longevity

What Life's Essential 8 predicts about living to 100

Nutrition

Why Ozempic and Wegovy weight-loss plateaus happen

Lab technician handling a powdered supplement sample in a sterile testing room.

Does creatine cause hair loss? What the evidence actually shows

A 2025 randomized trial found no sign that standard-dose creatine raised DHT or worsened hair-follicle measures over 12 weeks.

Amber vitamin capsules spilling from a glass jar on a white surface

Why vitamin D2 may lower vitamin D3 levels

Abstract molecular model illustrating magnesium biology in sleep and stress research

Can magnesium supplements lower cortisol? What the evidence says

Vitamin D and calcium supplement capsules on a neutral surface

Vitamin D, calcium do not prevent fractures in most older adults

Berberine side effects: what trials say about GI upset and safety

What berberine side effects show up most often?

Unlabelled white container and scoop beside creatine powder.

Creatine gummies vs powder: what the evidence says

Powder still has the clearer research base, while creatine gummies raise extra questions about stability, label accuracy, and shelf life.

Does creatine cause hair loss? What the evidence actually shows

Is zone 2 cardio really best for metabolic health?

Frontiers performance meta-analysis figure

Does creatine reduce inflammation? What the 2026 evidence actually shows

What Life's Essential 8 predicts about living to 100

Scientific illustration of NAD+ molecular structure and cellular aging concepts

Can NMN, NAD+ and resveratrol actually slow aging? Here's what the human evidence says

A mouse study puts gut particles at the center of aging

Shirtless man standing in a freezing lake near Ludvika, Sweden, surrounded by snow and ice during winter cold water immersion

Cold Plunges and Your Brain: What the Science Actually Shows

Detailed close-up of aged black garlic cloves on a dark background

Aged garlic compound nudges the fat-brain-muscle axis longevity researchers chase

Abstract representation of molecular structures and biological pathways in vibrant colors

Longevity supplement NOVOS Core improved vascular aging markers in first human trial

Psyllium husk for constipation hero image

Psyllium husk for constipation: what the evidence says

Trial and meta-analysis evidence suggests psyllium can help chronic constipation, especially for stool softness and regularity, but dose, timing and fluid intake matter.

A close-up of fibrous plant-based ingredients representing prebiotic inulin

Inulin for knee osteoarthritis: what the 2026 trial found

Petri dishes and pipette illustrating gut microbiome research

Why prebiotics may work differently on different guts

Petri dishes showing bacterial growth in a laboratory, illustrating microbiome research.

How a few medical visits reshaped gut microbes in remote Amazonian communities

Could infant gut microbes shape later ADHD risk?

Why Ozempic and Wegovy weight-loss plateaus happen

Ozempic weight-loss plateaus may reflect uneven brain-cell signalling, a new NIH mouse study suggests, though the finding is not yet clinical proof.

Semaglutide injection pen, illustrating GLP-1 drugs discussed in side-effect research.

What the Ozempic Reddit study can and cannot tell us

Watermelon slices and whole watermelon on a tabletop

Does watermelon improve diet quality or heart health?

Colorful molecular model illustrating branched-chain amino acid metabolism

BCAA metabolism and obesity: what the new Nature review found

Lion's mane mushroom close-up used as the story hero image

Lion's mane and memory: what human trials actually show

Abstract neural network illustration for a story about vitamin B12 and brain aging

Why 'normal' vitamin B12 may miss brain aging risk

Comprehensive set of brain MRI scans highlighting cranial anatomy for medical use.

Why common dementia risks may hit women harder

Abstract illustration of creatine and sleep-loss cognition

Can creatine blunt sleep-loss brain fog? The 2026 study

Abstract brain and nutrient concept for choline anxiety analysis

Lower brain choline may mark anxiety, not a supplement fix

Omega-3 supplements accelerated cognitive decline in older adults, study finds

Abstract scientific illustration related to brain aging and hypothalamic signalling

Could D-serine help slow brain aging? What the Menin mouse study found

D-serine and brain aging drew fresh attention after a mouse study tied hypothalamic Menin loss to memory decline, but human evidence is still thin.

How childhood junk food may rewire the brain for life

Close-up of pipettes and sample tubes in a laboratory, illustrating proteomic aging research.

What proteomic aging clocks can really tell us about biological age

Vitamin D, calcium do not prevent fractures in most older adults

Abstract DNA strands used to illustrate the paper's focus on repair pathways in aging neurons

How APOE2 helps neurons repair DNA and resist aging

Can vitamin D help you sleep? What the evidence says

Vitamin D may matter for sleep in some people, but the human evidence still does not support it as a general sleep aid.

Smartwatch sleep-tracking display used as an illustration for consumer sleep data.

How accurate are sleep trackers? What the 2026 evidence says

Can saffron help you sleep? What the evidence says

The Sleep Sweet Spot: 6 to 8 Hours Slows Biological Ageing Across 17 Organs

Can gut bacteria predict bone loss in hyperparathyroidism?

Laboratory plant sample illustrating research into ashwagandha and cortisol

Can ashwagandha lower cortisol? What the 2026 evidence says

Seaweed arranged in bowls and dishes, illustrating iodine-rich sea vegetables discussed in thyroid health research

Seaweed for thyroid health: what the iodine evidence says

Laboratory desk with microscope and notes, illustrating evidence-based thyroid research

Do thyroid support supplements actually help? What the evidence says

Can Allegra and Pepcid ease PMDD and menopause symptoms?

Close-up laboratory-style image suggesting creatine and menopause research

Can creatine help during menopause? What the evidence says

Assorted legumes, vegetables, nuts, and grains arranged on white plates

Plant-Based Diets Match Omnivore Diets for Athletic Performance, Review Finds

A 2025 state-of-the-art review in the American Journal of Lifestyle Medicine finds plant-based eating patterns are non-inferior to omnivore diets for athletic performance and muscle protein synthesis. The strongest supplement evidence supports creatine, caffeine, and protein.

Close-up of white supplement tablets on a clean surface

The Best Magnesium Supplements of 2026, According to Experts

Variety of capsules and powders arranged on a green backdrop

How To Choose the Right Magnesium Supplement for You

Closeup of a colorful molecular model illustrating abstract scientific concepts

The Vitalspell brief

Evidence-based supplement science — weekly in your inbox.

Can gut bacteria predict bone loss in hyperparathyroidism?

Can vitamin D help you sleep? What the evidence says

What Life's Essential 8 predicts about living to 100

Why Ozempic and Wegovy weight-loss plateaus happen

Does creatine cause hair loss? What the evidence actually shows

Why vitamin D2 may lower vitamin D3 levels

Can magnesium supplements lower cortisol? What the evidence says

Vitamin D, calcium do not prevent fractures in most older adults

What berberine side effects show up most often?

Creatine gummies vs powder: what the evidence says

Does creatine cause hair loss? What the evidence actually shows

Is zone 2 cardio really best for metabolic health?

Does creatine reduce inflammation? What the 2026 evidence actually shows

What Life's Essential 8 predicts about living to 100

Can NMN, NAD+ and resveratrol actually slow aging? Here's what the human evidence says

A mouse study puts gut particles at the center of aging

Cold Plunges and Your Brain: What the Science Actually Shows

Aged garlic compound nudges the fat-brain-muscle axis longevity researchers chase

Longevity supplement NOVOS Core improved vascular aging markers in first human trial

Psyllium husk for constipation: what the evidence says

Inulin for knee osteoarthritis: what the 2026 trial found

Why prebiotics may work differently on different guts

How a few medical visits reshaped gut microbes in remote Amazonian communities

Could infant gut microbes shape later ADHD risk?

Why Ozempic and Wegovy weight-loss plateaus happen

What the Ozempic Reddit study can and cannot tell us

Does watermelon improve diet quality or heart health?

BCAA metabolism and obesity: what the new Nature review found

Lion's mane and memory: what human trials actually show

Why 'normal' vitamin B12 may miss brain aging risk

Why common dementia risks may hit women harder

Can creatine blunt sleep-loss brain fog? The 2026 study

Lower brain choline may mark anxiety, not a supplement fix

Omega-3 supplements accelerated cognitive decline in older adults, study finds

Could D-serine help slow brain aging? What the Menin mouse study found

How childhood junk food may rewire the brain for life

What proteomic aging clocks can really tell us about biological age

Vitamin D, calcium do not prevent fractures in most older adults

How APOE2 helps neurons repair DNA and resist aging

Can vitamin D help you sleep? What the evidence says

How accurate are sleep trackers? What the 2026 evidence says

Can saffron help you sleep? What the evidence says

The Sleep Sweet Spot: 6 to 8 Hours Slows Biological Ageing Across 17 Organs

Can gut bacteria predict bone loss in hyperparathyroidism?

Can ashwagandha lower cortisol? What the 2026 evidence says

Seaweed for thyroid health: what the iodine evidence says

Do thyroid support supplements actually help? What the evidence says

Can Allegra and Pepcid ease PMDD and menopause symptoms?

Can creatine help during menopause? What the evidence says

Plant-Based Diets Match Omnivore Diets for Athletic Performance, Review Finds

The Best Magnesium Supplements of 2026, According to Experts

How To Choose the Right Magnesium Supplement for You

Vitamin D plus K2 acts like a drug, not a supplement

Can gut bacteria predict bone loss in hyperparathyroidism?

Can vitamin D help you sleep? What the evidence says

What Life's Essential 8 predicts about living to 100

Why Ozempic and Wegovy weight-loss plateaus happen

What the Ozempic Reddit study can and cannot tell us

Psyllium husk for constipation: what the evidence says

Lion's mane and memory: what human trials actually show

Could D-serine help slow brain aging? What the Menin mouse study found

Can ashwagandha lower cortisol? What the 2026 evidence says

The Vitalspell brief